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CORE RESEARCH SERVICES

GENOMICS AND BIOINFORMATICS

We provide a full complement of genomics and proprietary bioinformatics tools that serves as the capstone of our technologies to support the efforts of clients in human and animal health as well as agricultural and environmental fields.

This suite covers (a) microbial genome sequencing and annotation; (b) metagenomic analysis both by targeted and shotgun sequencing; (c) functional bioinformatics analysis at metabolic, pathway, community and expression levels; and (d) custom annotation and other bioinformatics services of genomic or metagenomic data using proprietary and public domain databases.

MICROBIAL SERVICES AND TOOLS

We collect, assemble and analyze microbial organisms from environmental, clinical, metagenomic other sources for in-house research, development or commercial-stage culture collections, with cloud-based database solutions for strain metadata, genome sequence, taxonomic, phenotypic and genotypic results, and curated information. Full service or a la carte, with collaborative project planning and software customization, and specialized handling of actinobacteria and anaerobes.

These services are supported by extensive expertise and practical experience in such diverse areas as clinical microbiology, microbial characterization and diversity and drug discovery.

OUR CAPABILITIES

ANTIBIOTIC RESISTANCE

  • Spontaneous Mutation Frequency
  • Serial Transfer/Passage
  • Phenotypic Drug Resistance Characterization
  • Whole Genome Drug Resistance Characterization

BIOINFORMATICS ANALYSES

  • Genomic
  • Metagenomic
  • Microbiomic
  • Transcriptomic
  • Epigenomic

ANTIBIOTIC DISCOVERY / EVALUATION

  • Broth or Agar Based MIC & MBC Determination
  • Bactericidal/Bacteriostatic Assessment
  • Kill-Curve
  • Post-Antibiotic Effect
  • Bacterial Persistence
  • Antibacterial Synergy/Antagonism
  • Minimal Biofilm Eradication Concentration
  • Spore Preparation
  • Sporicidal Assay

PRE-CLINICAL & CLINICAL MICROBIOME IMPACT STUDIES

  • Experimental and Study Design
  • Microbiome/Metagenome Data Generation & Analysis
  • Cultivation and Characterization of Target Organisms
  • Microbiome Repository and Database

MICROBIAL GENOME SEQUENCING & ANNOTATION

  • Bacterial
  • Fungal
  • Other Eukaryotes
  • Viral

CUSTOM SERVICES

  • Custom Synthesis of Tagged Bacteria & Fungi
  • Clinical Isolate Repository
  • Mock Community Construction & Validation
  • Microbiome Sample Preparation and QC
  • Anaerobic Microbiology
  • Adhesion/Invasion Assays
  • Mammalian Cytotoxicity Assay

For inquiries on research services or collaborations, please contact us by filling the form below.

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